This proposal outlines steps for the Federal Government to establish a national initiative to accelerate the implementation of rigorous computer science (CS) education for preschool through 12th grade (P-12) students in the United States. The initiative should include investments in evidence-based education pathways that incorporate computational thinking, computer programming (coding), cybersecurity, data science, social impacts of computing, and ethics, and prepare students for future careers working with technologies such as artificial intelligence (AI), machine learning, virtual/augmented reality, autonomous vehicles, automation, cybersecurity and other emerging and future technologies. This initiative is critical to enhancing the United States’ global competitiveness, economic growth, and technological innovation, while addressing pressing social challenges such as healthcare, social mobility, climate change and national security in an increasingly technology-driven and innovation-based global economy.